What is the half-life of an IgG antibody?

The half-life of an IgG antibody is typically around 21 to 28 days. This range is significant because it reflects the longevity and stability of the IgG antibodies within the body, which are crucial for the immune response. IgG is the most abundant type of antibody in the bloodstream, providing long-term protection against pathogens.

Understanding the half-life is important in various clinical contexts, including vaccination responses and the monitoring of immunoglobulin therapies. A half-life of 21 to 28 days indicates that after this period, the concentration of antibodies in the blood reduces by half, impacting both the assessment of immune function and the timing of further interventions if necessary.