Which two nutrients aid in the prevention of calcium oxalate kidney stones?

Vitamin B6 and Magnesium are important in the prevention of calcium oxalate kidney stones due to their roles in metabolic processes and their influence on urinary composition.

Vitamin B6 is essential for the metabolism of amino acids and has been shown to help reduce levels of oxalate in the urine. High levels of oxalate can combine with calcium, leading to the formation of calcium oxalate stones. By aiding in the metabolism that breaks down oxalates, Vitamin B6 helps to diminish the likelihood of stone formation.

Magnesium contributes by inhibiting the crystallization of calcium oxalate in the urine. It helps to keep oxalate levels in check and competes with calcium for binding sites, reducing the likelihood that calcium will combine with oxalate. Adequate magnesium levels are associated with a lower risk of stone formation, as it can help reduce the concentration of substances that promote stone formation in the urinary tract.

The other options do not directly contribute to the prevention of calcium oxalate kidney stones in the same way. Therefore, the combination of Vitamin B6 and Magnesium provides a synergistic effect that targets the underlying pathways associated with kidney stone formation.