Which vitamin serves as the major antioxidant in the fluid lining of airway surfaces?

Vitamin C is known to play a significant role as a major antioxidant in the fluid lining of airway surfaces. Its presence in these areas helps protect lung tissues from oxidative stress caused by pollutants and pathogens. This antioxidant capability is crucial because the respiratory system is frequently exposed to environmental toxins and irritants that can lead to inflammation and damage.

Vitamin C, being water-soluble, can efficiently neutralize free radicals in the aqueous environments of the lungs. It also contributes to the synthesis of collagen, which is vital for maintaining the structural integrity of lung tissues. In addition to its direct antioxidant function, Vitamin C supports the immune system, which is particularly important for maintaining respiratory health.

Other vitamins, while they have their own roles within the body, do not specifically serve as the primary antioxidant in the airway lining. Vitamin A is more associated with vision and immune function; Vitamin E is a significant fat-soluble antioxidant, but its primary functions are usually related to protecting cell membranes rather than the airway surface. Vitamin B12 is essential for nerve health and red blood cell formation but does not function as an antioxidant in this context.